Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis.
Stochastic fluctuations in gene expression give rise to cell-to-cell variability in protein levels which can potentially cause variability in cellular phenotype. For TRAIL (TNF-related apoptosis-inducing ligand) variability manifests itself as dramatic differences in the time between ligand exposure...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/1a70568a02dd49bdba33d80b7ca035f9 |
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