Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis.
Stochastic fluctuations in gene expression give rise to cell-to-cell variability in protein levels which can potentially cause variability in cellular phenotype. For TRAIL (TNF-related apoptosis-inducing ligand) variability manifests itself as dramatic differences in the time between ligand exposure...
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Auteurs principaux: | , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/1a70568a02dd49bdba33d80b7ca035f9 |
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