Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis.

Stochastic fluctuations in gene expression give rise to cell-to-cell variability in protein levels which can potentially cause variability in cellular phenotype. For TRAIL (TNF-related apoptosis-inducing ligand) variability manifests itself as dramatic differences in the time between ligand exposure...

Full description

Saved in:
Bibliographic Details
Main Authors: Suzanne Gaudet, Sabrina L Spencer, William W Chen, Peter K Sorger
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Online Access:https://doaj.org/article/1a70568a02dd49bdba33d80b7ca035f9
Tags: Add Tag
No Tags, Be the first to tag this record!