Exon first nucleotide mutations in splicing: evaluation of in silico prediction tools.
Mutations in the first nucleotide of exons (E(+1)) mostly affect pre-mRNA splicing when found in AG-dependent 3' splice sites, whereas AG-independent splice sites are more resistant. The AG-dependency, however, may be difficult to assess just from primary sequence data as it depends on the qual...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2014
|
| Subjects: | |
| Online Access: | https://doaj.org/article/1a828e23d9c641e8b2d7b6964207b25e |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|