DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells

Caspase independent alternative cell death (ACD) pathways exist, but have been largely investigated under non-physiological conditions. Here, the authors show that Drosophila primordial germ cells normally elicit DNase II-dependent DNA damage, triggering a parthanatos-like ACD pathway.

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Autores principales:	Lama Tarayrah-Ibraheim, Elital Chass Maurice, Guy Hadary, Sharon Ben-Hur, Alina Kolpakova, Tslil Braun, Yoav Peleg, Keren Yacobi-Sharon, Eli Arama
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1a9965c07ebe4575a42eb34b43c4877a
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spelling	oai:doaj.org-article:1a9965c07ebe4575a42eb34b43c4877a2021-12-02T14:30:27ZDNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells10.1038/s41467-021-22622-12041-1723https://doaj.org/article/1a9965c07ebe4575a42eb34b43c4877a2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22622-1https://doaj.org/toc/2041-1723Caspase independent alternative cell death (ACD) pathways exist, but have been largely investigated under non-physiological conditions. Here, the authors show that Drosophila primordial germ cells normally elicit DNase II-dependent DNA damage, triggering a parthanatos-like ACD pathway.Lama Tarayrah-IbraheimElital Chass MauriceGuy HadarySharon Ben-HurAlina KolpakovaTslil BraunYoav PelegKeren Yacobi-SharonEli AramaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lama Tarayrah-Ibraheim Elital Chass Maurice Guy Hadary Sharon Ben-Hur Alina Kolpakova Tslil Braun Yoav Peleg Keren Yacobi-Sharon Eli Arama DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells
description	Caspase independent alternative cell death (ACD) pathways exist, but have been largely investigated under non-physiological conditions. Here, the authors show that Drosophila primordial germ cells normally elicit DNase II-dependent DNA damage, triggering a parthanatos-like ACD pathway.
format	article
author	Lama Tarayrah-Ibraheim Elital Chass Maurice Guy Hadary Sharon Ben-Hur Alina Kolpakova Tslil Braun Yoav Peleg Keren Yacobi-Sharon Eli Arama
author_facet	Lama Tarayrah-Ibraheim Elital Chass Maurice Guy Hadary Sharon Ben-Hur Alina Kolpakova Tslil Braun Yoav Peleg Keren Yacobi-Sharon Eli Arama
author_sort	Lama Tarayrah-Ibraheim
title	DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells
title_short	DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells
title_full	DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells
title_fullStr	DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells
title_full_unstemmed	DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells
title_sort	dnase ii mediates a parthanatos-like developmental cell death pathway in drosophila primordial germ cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1a9965c07ebe4575a42eb34b43c4877a
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DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells

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