Angiotensin converting enzyme 2 is a novel target of the γ-secretase complex

Abstract Angiotensin converting enzyme 2 (ACE2) is a key regulator of the renin-angiotensin system, but also the functional receptor of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Based on structural similarity with other γ-secretase (γS) targets, we hypothesized that ACE2 may...

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Autores principales: Alberto Bartolomé, Jiani Liang, Pengfei Wang, David D. Ho, Utpal B. Pajvani
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1aa72151492a40cfb224c6aefc913fef
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