Angiotensin converting enzyme 2 is a novel target of the γ-secretase complex
Abstract Angiotensin converting enzyme 2 (ACE2) is a key regulator of the renin-angiotensin system, but also the functional receptor of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Based on structural similarity with other γ-secretase (γS) targets, we hypothesized that ACE2 may...
Guardado en:
Autores principales: | Alberto Bartolomé, Jiani Liang, Pengfei Wang, David D. Ho, Utpal B. Pajvani |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1aa72151492a40cfb224c6aefc913fef |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Visualizing active enzyme complexes using a photoreactive inhibitor for proximity ligation--application on γ-secretase.
por: Sophia Schedin-Weiss, et al.
Publicado: (2013) -
Mechanism of intramembrane cleavage of alcadeins by γ-secretase.
por: Yi Piao, et al.
Publicado: (2013) -
Usage of Angiotensin-Converting Enzyme Inhibitor or Angiotensin II Receptor Blocker in Hypertension Intracerebral Hemorrhage
por: Zhang C, et al.
Publicado: (2021) -
Smoking and Angiotensin-converting Enzyme Inhibitor/Angiotensin Receptor Blocker Cessation to Limit Coronavirus Disease 2019
por: Marco Rossato, et al.
Publicado: (2020) -
Presenilin/γ-secretase regulates neurexin processing at synapses.
por: Carlos A Saura, et al.
Publicado: (2011)