Alpha 2 Na+,K+-ATPase silencing induces loss of inflammatory response and ouabain protection in glial cells

Abstract Ouabain (OUA) is a cardiac glycoside that binds to Na+,K+-ATPase (NKA), a conserved membrane protein that controls cell transmembrane ionic concentrations and requires ATP hydrolysis. At nM concentrations, OUA activates signaling pathways that are not related to its typical inhibitory effec...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Paula F. Kinoshita, Lidia M. Yshii, Ana Maria M. Orellana, Amanda G. Paixão, Andrea R. Vasconcelos, Larissa de Sá Lima, Elisa M. Kawamoto, Cristoforo Scavone
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
R
Q
Acceso en línea:https://doaj.org/article/1adf6f5253cc4c8bb05fb066494c48ed
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!