Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma

Bondoc et al perform single-cell RNA-Seq profiling of Hepatoblastoma, background liver, and patient-derived xenografts to investigate cell-type heterogeneity and characterise the driver malignant cell cluster.

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Autores principales: Alexander Bondoc, Kathryn Glaser, Kang Jin, Charissa Lake, Stefano Cairo, James Geller, Gregory Tiao, Bruce Aronow
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1ae5ebea38d9407bb8359463ea860fc8
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