Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma

Bondoc et al perform single-cell RNA-Seq profiling of Hepatoblastoma, background liver, and patient-derived xenografts to investigate cell-type heterogeneity and characterise the driver malignant cell cluster.

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Autores principales:	Alexander Bondoc, Kathryn Glaser, Kang Jin, Charissa Lake, Stefano Cairo, James Geller, Gregory Tiao, Bruce Aronow
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/1ae5ebea38d9407bb8359463ea860fc8
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spelling	oai:doaj.org-article:1ae5ebea38d9407bb8359463ea860fc82021-12-02T19:13:48ZIdentification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma10.1038/s42003-021-02562-82399-3642https://doaj.org/article/1ae5ebea38d9407bb8359463ea860fc82021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02562-8https://doaj.org/toc/2399-3642Bondoc et al perform single-cell RNA-Seq profiling of Hepatoblastoma, background liver, and patient-derived xenografts to investigate cell-type heterogeneity and characterise the driver malignant cell cluster.Alexander BondocKathryn GlaserKang JinCharissa LakeStefano CairoJames GellerGregory TiaoBruce AronowNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Alexander Bondoc Kathryn Glaser Kang Jin Charissa Lake Stefano Cairo James Geller Gregory Tiao Bruce Aronow Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma
description	Bondoc et al perform single-cell RNA-Seq profiling of Hepatoblastoma, background liver, and patient-derived xenografts to investigate cell-type heterogeneity and characterise the driver malignant cell cluster.
format	article
author	Alexander Bondoc Kathryn Glaser Kang Jin Charissa Lake Stefano Cairo James Geller Gregory Tiao Bruce Aronow
author_facet	Alexander Bondoc Kathryn Glaser Kang Jin Charissa Lake Stefano Cairo James Geller Gregory Tiao Bruce Aronow
author_sort	Alexander Bondoc
title	Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma
title_short	Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma
title_full	Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma
title_fullStr	Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma
title_full_unstemmed	Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma
title_sort	identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1ae5ebea38d9407bb8359463ea860fc8
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Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma

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