Signaling through the S1P−S1PR Axis in the Gut, the Immune and the Central Nervous System in Multiple Sclerosis: Implication for Pathogenesis and Treatment
Sphingosine 1-phosphate (S1P) is a signaling molecule with complex biological functions that are exerted through the activation of sphingosine 1-phosphate receptors 1–5 (S1PR1–5). S1PR expression is necessary for cell proliferation, angiogenesis, neurogenesis and, importantly, for the egress of lymp...
Guardado en:
Autores principales: | Simela Chatzikonstantinou, Vasiliki Poulidou, Marianthi Arnaoutoglou, Dimitrios Kazis, Ioannis Heliopoulos, Nikolaos Grigoriadis, Marina Boziki |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/1b0c7d85cb8f43609f39a7f1b9a5c267 |
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