Systematic prediction of drug resistance caused by transporter genes in cancer cells

Abstract To study the drug resistance problem caused by transporters, we leveraged multiple large-scale public data sets of drug sensitivity, cell line genetic and transcriptional profiles, and gene silencing experiments. Through systematic integration of these data sets, we built various machine le...

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Autores principales: Yao Shen, Zhipeng Yan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1b1666041b5b4e3fa52dc156b1a03cca
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