Identification of Novel Type Three Secretion System (T3SS) Inhibitors by Computational Methods and Anti-Salmonella Evaluations

Three type III secretion system (T3SS) inhibitors (compounds 5, 19, and 32) were identified by virtual screening and biological evaluation. These three compounds were evaluated against a panel of Salmonella species strains including S. enteritidis, S. typhi, S. typhimurium, S. paratyphi, and S. abor...

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Auteurs principaux: Yonghui Wang, Meihui Hou, Zhaodong Kan, Guanghui Zhang, Yunxia Li, Lei Zhou, Changfa Wang
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/1b1730a2dae54f99bd2132a4ddbe0c4f
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