Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans

Recent evidence has questioned the dogma of strict maternal transmission of mitochondrial DNA (mtDNA) in humans. Wei et al. saw no evidence of paternal transmission of mtDNA in 11,035 human trios, and show that nuclear-mitochondrial segments (NUMTs) can give the impression of paternal mtDNA transmis...

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Auteurs principaux: Wei Wei, Alistair T. Pagnamenta, Nicholas Gleadall, Alba Sanchis-Juan, Jonathan Stephens, John Broxholme, Salih Tuna, Christopher A. Odhams, Genomics England Research Consortium, NIHR BioResource, Carl Fratter, Ernest Turro, Mark J. Caulfield, Jenny C. Taylor, Shamima Rahman, Patrick F. Chinnery
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Science
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Accès en ligne:https://doaj.org/article/1b33ee54b03a414c950db059cdfe623d
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https://doaj.org/article/1b33ee54b03a414c950db059cdfe623d

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