The smfBox is an open-source platform for single-molecule FRET

Broad uptake of smFRET has been hindered by high instrument costs and a lack of open-source hardware and acquisition software. Here, the authors present the smfBox, a cost-effective open-source platform capable of measuring precise FRET efficiencies between dyes on freely diffusing single molecules.

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Bibliographic Details
Main Authors: Benjamin Ambrose, James M. Baxter, John Cully, Matthew Willmott, Elliot M. Steele, Benji C. Bateman, Marisa L. Martin-Fernandez, Ashley Cadby, Jonathan Shewring, Marleen Aaldering, Timothy D. Craggs
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/1b8fcae7f02c497fbb6bd0987c70a694
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