The smfBox is an open-source platform for single-molecule FRET
Broad uptake of smFRET has been hindered by high instrument costs and a lack of open-source hardware and acquisition software. Here, the authors present the smfBox, a cost-effective open-source platform capable of measuring precise FRET efficiencies between dyes on freely diffusing single molecules.
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Nature Portfolio
2020
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oai:doaj.org-article:1b8fcae7f02c497fbb6bd0987c70a6942021-12-02T17:31:25ZThe smfBox is an open-source platform for single-molecule FRET10.1038/s41467-020-19468-42041-1723https://doaj.org/article/1b8fcae7f02c497fbb6bd0987c70a6942020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19468-4https://doaj.org/toc/2041-1723Broad uptake of smFRET has been hindered by high instrument costs and a lack of open-source hardware and acquisition software. Here, the authors present the smfBox, a cost-effective open-source platform capable of measuring precise FRET efficiencies between dyes on freely diffusing single molecules.Benjamin AmbroseJames M. BaxterJohn CullyMatthew WillmottElliot M. SteeleBenji C. BatemanMarisa L. Martin-FernandezAshley CadbyJonathan ShewringMarleen AalderingTimothy D. CraggsNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-6 (2020) |
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Science Q Benjamin Ambrose James M. Baxter John Cully Matthew Willmott Elliot M. Steele Benji C. Bateman Marisa L. Martin-Fernandez Ashley Cadby Jonathan Shewring Marleen Aaldering Timothy D. Craggs The smfBox is an open-source platform for single-molecule FRET |
description |
Broad uptake of smFRET has been hindered by high instrument costs and a lack of open-source hardware and acquisition software. Here, the authors present the smfBox, a cost-effective open-source platform capable of measuring precise FRET efficiencies between dyes on freely diffusing single molecules. |
format |
article |
author |
Benjamin Ambrose James M. Baxter John Cully Matthew Willmott Elliot M. Steele Benji C. Bateman Marisa L. Martin-Fernandez Ashley Cadby Jonathan Shewring Marleen Aaldering Timothy D. Craggs |
author_facet |
Benjamin Ambrose James M. Baxter John Cully Matthew Willmott Elliot M. Steele Benji C. Bateman Marisa L. Martin-Fernandez Ashley Cadby Jonathan Shewring Marleen Aaldering Timothy D. Craggs |
author_sort |
Benjamin Ambrose |
title |
The smfBox is an open-source platform for single-molecule FRET |
title_short |
The smfBox is an open-source platform for single-molecule FRET |
title_full |
The smfBox is an open-source platform for single-molecule FRET |
title_fullStr |
The smfBox is an open-source platform for single-molecule FRET |
title_full_unstemmed |
The smfBox is an open-source platform for single-molecule FRET |
title_sort |
smfbox is an open-source platform for single-molecule fret |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/1b8fcae7f02c497fbb6bd0987c70a694 |
work_keys_str_mv |
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