The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy indian adolescents.

The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy indian adolescents.

<h4>Background</h4>QuantiFERON-TB Gold In-Tube (QFT) is an IFNγ-release assay used in the diagnosis of Mycobacterium tuberculosis (MTB) infection. The risk of TB progression increases with the magnitude of the MTB-specific IFNγ-response. QFT reversion, also associated with low Tuberculin...

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Détails bibliographiques
Auteurs principaux: Synne Jenum, Harleen M S Grewal, David A Hokey, John Kenneth, Mario Vaz, Timothy Mark Doherty, Frode Lars Jahnsen, TB Trials Study Group
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/1b9b875ee60b4e01b7cd37647e483ff0
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Internet

https://doaj.org/article/1b9b875ee60b4e01b7cd37647e483ff0

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