Cryo-EM structure of 5-HT3A receptor in its resting conformation

Cryo-EM structure of 5-HT3A receptor in its resting conformation

Serotonin receptor (5-HT3AR), a pentameric ligand-gated ion channel, regulates numerous gastrointestinal functions. Here the authors provide a cryo-electron microscopic structure from the full-length 5-HT3AR in the apo-state which corresponds to a resting conformation of the channel.

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Bibliographic Details
Main Authors: Sandip Basak, Yvonne Gicheru, Amrita Samanta, Sudheer Kumar Molugu, Wei Huang, Maria la de Fuente, Taylor Hughes, Derek J. Taylor, Marvin T. Nieman, Vera Moiseenkova-Bell, Sudha Chakrapani
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/1bb90dff34df4dafbd0d19b7edd091cb
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https://doaj.org/article/1bb90dff34df4dafbd0d19b7edd091cb

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