Perturbation of microRNAs in rat heart during chronic doxorubicin treatment.

Perturbation of microRNAs in rat heart during chronic doxorubicin treatment.

Anti-cancer therapy based on anthracyclines (DNA intercalating Topoisomerase II inhibitors) is limited by adverse effects of these compounds on the cardiovascular system, ultimately causing heart failure. Despite extensive investigations into the effects of doxorubicin on the cardiovascular system,...

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Bibliographic Details
Main Authors: Caterina Vacchi-Suzzi, Yasmina Bauer, Brian R Berridge, Sandrine Bongiovanni, Kevin Gerrish, Hisham K Hamadeh, Martin Letzkus, Jonathan Lyon, Jonathan Moggs, Richard S Paules, François Pognan, Frank Staedtler, Martin P Vidgeon-Hart, Olivier Grenet, Philippe Couttet
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/1bf1e6df5257478dabeac3b061a4a4f0
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https://doaj.org/article/1bf1e6df5257478dabeac3b061a4a4f0

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