Optimization of Personalized Amlodipine Dosing Strategies for Children Based on Pharmacokinetic Data from Chinese Male Adults and PBPK Modeling

For children, a special population who are continuously developing, a reasonable dosing strategy is the key to clinical therapy. Accurate dose predictions can help maximize efficacy and minimize pain in pediatrics. <b>Methods:</b> This study collected amlodipine pharmacokinetics (PK) dat...

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Autores principales: Xiaolu Han, Xiaoxuan Hong, Xianfu Li, Yuxi Wang, Zengming Wang, Aiping Zheng
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/1bff174e425343709d687d318bca480f
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