Optimization of Personalized Amlodipine Dosing Strategies for Children Based on Pharmacokinetic Data from Chinese Male Adults and PBPK Modeling
For children, a special population who are continuously developing, a reasonable dosing strategy is the key to clinical therapy. Accurate dose predictions can help maximize efficacy and minimize pain in pediatrics. <b>Methods:</b> This study collected amlodipine pharmacokinetics (PK) dat...
Guardado en:
Autores principales: | Xiaolu Han, Xiaoxuan Hong, Xianfu Li, Yuxi Wang, Zengming Wang, Aiping Zheng |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1bff174e425343709d687d318bca480f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
PBPK Modeling and Simulation of Antibiotics Amikacin, Gentamicin, Tobramycin, and Vancomycin Used in Hospital Practice
por: Abigail Ferreira, et al.
Publicado: (2021) -
PBPK Modeling and Simulation and Therapeutic Drug Monitoring: Possible Ways for Antibiotic Dose Adjustment
por: Abigail Ferreira, et al.
Publicado: (2021) -
Effects of different enantiomers of amlodipine on lipid profiles and vasomotor factors in atherosclerotic rabbits
por: Zhang Jing, et al.
Publicado: (2021) -
SIMULTANEOUS QUANTITATION OF OLMESARTAN MEDOXOMIL AND AMLODIPINE BESYLATE IN COMBINED TABLETS USING HPLC
por: QUTAB,SYED SHANAZ, et al.
Publicado: (2009) -
Combination of inflammatory and amlodipine induced gingival overgrowth in a patient with cardiovascular disease
por: Mohan Kumar Pasupuleti, et al.
Publicado: (2013)