Essential role of TOSO/FAIM3 in intestinal IgM reverse transcytosis

Summary: Secretory immunoglobulin A (SIgA) can travel to and from the lumen and transport antigen to subepithelial cells. However, IgM can also multimerize into functional secretory component-bound immunoglobulin. While it is already known that both SIgA and SIgM undergo transcytosis to be secreted...

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Autores principales: Nicolas Rochereau, Eva Michaud, Louis Waeckel, Martin Killian, Rémi Gayet, Roman Goguyer-Deschaumes, Xavier Roblin, Gilles Biolley, Blaise Corthésy, Stéphane Paul
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
IgM
Acceso en línea:https://doaj.org/article/1c0d9dd7c688430d9d5f4ebbadbdf92f
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