Not a Simple Tether: Binding of <named-content content-type="genus-species">Toxoplasma gondii</named-content> AMA1 to RON2 during Invasion Protects AMA1 from Rhomboid-Mediated Cleavage and Leads to Dephosphorylation of Its Cytosolic Tail
ABSTRACT Apical membrane antigen 1 (AMA1) is a receptor protein on the surface of Toxoplasma gondii that plays a critical role in host cell invasion. The ligand to which T. gondii AMA1 (TgAMA1) binds, TgRON2, is secreted into the host cell membrane by the parasite during the early stages of invasion...
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| Autores principales: | , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
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American Society for Microbiology
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/1c59c1812b074a398410eb203c0aa4eb |
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