Insights into substrate recognition and specificity for IgG by Endoglycosidase S2.
Antibodies bind foreign antigens with high affinity and specificity leading to their neutralization and/or clearance by the immune system. The conserved N-glycan on IgG has significant impact on antibody effector function, with the endoglycosidases of Streptococcus pyogenes deglycosylating the IgG t...
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Auteurs principaux: | , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2021
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Accès en ligne: | https://doaj.org/article/1c5a1fb3a1a0497cac4852104caef0b6 |
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