Identification of small molecule inhibitors of Interleukin-18

Abstract Interleukin-18 (IL-18) is a pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. IL-18 plays an important role in host innate and adaptive immune defense but its aberrant activities are also associated with inflammatory diseases such as rheumatoid arthritis and Crohn...

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Autores principales: Brian Krumm, Xiangzhi Meng, Yan Xiang, Junpeng Deng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/1c88fdede59c408984d6dcc9a8111a5e
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