Identification of small molecule inhibitors of Interleukin-18
Abstract Interleukin-18 (IL-18) is a pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. IL-18 plays an important role in host innate and adaptive immune defense but its aberrant activities are also associated with inflammatory diseases such as rheumatoid arthritis and Crohn...
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Autores principales: | Brian Krumm, Xiangzhi Meng, Yan Xiang, Junpeng Deng |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/1c88fdede59c408984d6dcc9a8111a5e |
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