Dynamic patterns of DNA methylation in the normal prostate epithelial differentiation program are targets of aberrant methylation in prostate cancer

Abstract Understanding the epigenetic control of normal differentiation programs might yield principal information about critical regulatory states that are disturbed in cancer. We utilized the established non-malignant HPr1-AR prostate epithelial cell model that upon androgen exposure commits to a...

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Auteurs principaux: Mark D. Long, Vineet K. Dhiman, Hayley C. Affronti, Qiang Hu, Song Liu, Dominic J. Smiraglia
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/1c9873b8918b4954ad0cf088d4af5c1d
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