Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID.

<h4>Background</h4>Despite considerable effort, the genetic factors responsible for >90% of the antibody deficiency syndromes IgAD and CVID remain elusive. To produce a functionally diverse antibody repertoire B lymphocytes undergo class switch recombination. This process is initiated...

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Auteurs principaux: Steven M Offer, Qiang Pan-Hammarström, Lennart Hammarström, Reuben S Harris
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/1cb7b88ce5e7404c98fa92669dae6bed
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