The design of a Bayesian adaptive clinical trial of tranexamic acid in severely injured children
Abstract Background Trauma is the leading cause of death and disability in children in the USA. Tranexamic acid (TXA) reduces the blood transfusion requirements in adults and children during surgery. Several studies have evaluated TXA in adults with hemorrhagic trauma, but no randomized controlled t...
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Autores principales: | John M. VanBuren, T. Charles Casper, Daniel K. Nishijima, Nathan Kuppermann, Roger J. Lewis, J. Michael Dean, Anna McGlothlin, For the TIC-TOC Collaborators of the Pediatric Emergency Care Applied Research Network (PECARN) |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
BMC
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/1cc18e06b8e348a38442702dd6d5bb1c |
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