Interaction of the <i>Escherichia coli</i> HU Protein with Various Topological Forms of DNA

<i>E. coli</i> histone-like protein HU has been shown to interact with different topological forms of DNA. Using radiolabeled HU, we examine the effects of DNA supercoiling on HU–DNA interactions. We show that HU binds preferentially to negatively supercoiled DNA and that the affinity of...

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Détails bibliographiques
Auteurs principaux: Li Huang, Zhenfeng Zhang, Roger McMacken
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
HU
Accès en ligne:https://doaj.org/article/1cec0f66d91642efa482bce21fbe964f
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