Interaction of the <i>Escherichia coli</i> HU Protein with Various Topological Forms of DNA

<i>E. coli</i> histone-like protein HU has been shown to interact with different topological forms of DNA. Using radiolabeled HU, we examine the effects of DNA supercoiling on HU–DNA interactions. We show that HU binds preferentially to negatively supercoiled DNA and that the affinity of...

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Bibliographic Details
Main Authors: Li Huang, Zhenfeng Zhang, Roger McMacken
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
HU
Online Access:https://doaj.org/article/1cec0f66d91642efa482bce21fbe964f
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