Structure and function of the Orc1 BAH-nucleosome complex
The Origin Recognition Complex (ORC) plays conserved and diverse roles in eukaryotes. Here the authors present the structure of a chromatin interacting domain of yeast Orc1 in complex with the nucleosome core particle, revealing that Orc1 interacts with the histone H4 tail irrespective of K16 acetyl...
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Autores principales: | Pablo De Ioannes, Victor A. Leon, Zheng Kuang, Miao Wang, Jef D. Boeke, Andreas Hochwagen, Karim-Jean Armache |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/1cec6b48299e488d97d26035f5611a1a |
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