Intermolecular channels direct crystal orientation in mineralized collagen

Intermolecular channels direct crystal orientation in mineralized collagen

Mineralized collagen is the building block of bone but how the collagen directs hydroxyapatite formation remains unclear. Here, the authors demonstrate cylindrical pores in collagen and how the anisotropic growth of hydroxyapatite directs the orientation of crystal growth in mineralized collagen.

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Detalles Bibliográficos
Autores principales: YiFei Xu, Fabio Nudelman, E. Deniz Eren, Maarten J. M. Wirix, Bram Cantaert, Wouter H. Nijhuis, Daniel Hermida-Merino, Giuseppe Portale, Paul H. H. Bomans, Christian Ottmann, Heiner Friedrich, Wim Bras, Anat Akiva, Joseph P. R. O. Orgel, Fiona C. Meldrum, Nico Sommerdijk
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/1d1cee43ec3242e7916df4543ee0fb2a
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Sumario:Mineralized collagen is the building block of bone but how the collagen directs hydroxyapatite formation remains unclear. Here, the authors demonstrate cylindrical pores in collagen and how the anisotropic growth of hydroxyapatite directs the orientation of crystal growth in mineralized collagen.

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