Intermolecular channels direct crystal orientation in mineralized collagen

Mineralized collagen is the building block of bone but how the collagen directs hydroxyapatite formation remains unclear. Here, the authors demonstrate cylindrical pores in collagen and how the anisotropic growth of hydroxyapatite directs the orientation of crystal growth in mineralized collagen.

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Autores principales: YiFei Xu, Fabio Nudelman, E. Deniz Eren, Maarten J. M. Wirix, Bram Cantaert, Wouter H. Nijhuis, Daniel Hermida-Merino, Giuseppe Portale, Paul H. H. Bomans, Christian Ottmann, Heiner Friedrich, Wim Bras, Anat Akiva, Joseph P. R. O. Orgel, Fiona C. Meldrum, Nico Sommerdijk
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/1d1cee43ec3242e7916df4543ee0fb2a
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spelling oai:doaj.org-article:1d1cee43ec3242e7916df4543ee0fb2a2021-12-02T19:16:33ZIntermolecular channels direct crystal orientation in mineralized collagen10.1038/s41467-020-18846-22041-1723https://doaj.org/article/1d1cee43ec3242e7916df4543ee0fb2a2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18846-2https://doaj.org/toc/2041-1723Mineralized collagen is the building block of bone but how the collagen directs hydroxyapatite formation remains unclear. Here, the authors demonstrate cylindrical pores in collagen and how the anisotropic growth of hydroxyapatite directs the orientation of crystal growth in mineralized collagen.YiFei XuFabio NudelmanE. Deniz ErenMaarten J. M. WirixBram CantaertWouter H. NijhuisDaniel Hermida-MerinoGiuseppe PortalePaul H. H. BomansChristian OttmannHeiner FriedrichWim BrasAnat AkivaJoseph P. R. O. OrgelFiona C. MeldrumNico SommerdijkNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
YiFei Xu
Fabio Nudelman
E. Deniz Eren
Maarten J. M. Wirix
Bram Cantaert
Wouter H. Nijhuis
Daniel Hermida-Merino
Giuseppe Portale
Paul H. H. Bomans
Christian Ottmann
Heiner Friedrich
Wim Bras
Anat Akiva
Joseph P. R. O. Orgel
Fiona C. Meldrum
Nico Sommerdijk
Intermolecular channels direct crystal orientation in mineralized collagen
description Mineralized collagen is the building block of bone but how the collagen directs hydroxyapatite formation remains unclear. Here, the authors demonstrate cylindrical pores in collagen and how the anisotropic growth of hydroxyapatite directs the orientation of crystal growth in mineralized collagen.
format article
author YiFei Xu
Fabio Nudelman
E. Deniz Eren
Maarten J. M. Wirix
Bram Cantaert
Wouter H. Nijhuis
Daniel Hermida-Merino
Giuseppe Portale
Paul H. H. Bomans
Christian Ottmann
Heiner Friedrich
Wim Bras
Anat Akiva
Joseph P. R. O. Orgel
Fiona C. Meldrum
Nico Sommerdijk
author_facet YiFei Xu
Fabio Nudelman
E. Deniz Eren
Maarten J. M. Wirix
Bram Cantaert
Wouter H. Nijhuis
Daniel Hermida-Merino
Giuseppe Portale
Paul H. H. Bomans
Christian Ottmann
Heiner Friedrich
Wim Bras
Anat Akiva
Joseph P. R. O. Orgel
Fiona C. Meldrum
Nico Sommerdijk
author_sort YiFei Xu
title Intermolecular channels direct crystal orientation in mineralized collagen
title_short Intermolecular channels direct crystal orientation in mineralized collagen
title_full Intermolecular channels direct crystal orientation in mineralized collagen
title_fullStr Intermolecular channels direct crystal orientation in mineralized collagen
title_full_unstemmed Intermolecular channels direct crystal orientation in mineralized collagen
title_sort intermolecular channels direct crystal orientation in mineralized collagen
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/1d1cee43ec3242e7916df4543ee0fb2a
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