Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects.

<h4>Background</h4>Adult hippocampal neurogenesis has been implicated in the mechanism of antidepressant action, and neurotrophic factors can mediate the neurogenic changes underlying these effects. The neurotrophic factor neuregulin-1 (NRG1) is involved in many aspects of brain developm...

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Autores principales: Ian Mahar, Stephanie Tan, Maria Antonietta Davoli, Sergio Dominguez-Lopez, Calvin Qiang, Adeline Rachalski, Gustavo Turecki, Naguib Mechawar
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/1d30f46b6fa04af2a82f01b6af48e597
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