Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects.
<h4>Background</h4>Adult hippocampal neurogenesis has been implicated in the mechanism of antidepressant action, and neurotrophic factors can mediate the neurogenic changes underlying these effects. The neurotrophic factor neuregulin-1 (NRG1) is involved in many aspects of brain developm...
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Autores principales: | Ian Mahar, Stephanie Tan, Maria Antonietta Davoli, Sergio Dominguez-Lopez, Calvin Qiang, Adeline Rachalski, Gustavo Turecki, Naguib Mechawar |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/1d30f46b6fa04af2a82f01b6af48e597 |
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