A549 cells contain enlarged mitochondria with independently functional clustered mtDNA nucleoids.

Mitochondria are commonly viewed as highly elongated organelles with regularly spaced mtDNA genomes organized as compact nucleoids that generate the local transcripts essential for production of mitochondrial ribosomes and key components of the respiratory chain. In contrast, A549 human lung carcino...

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Autores principales: Aleksandrs Nasonovs, Miguel Garcia-Diaz, Daniel F Bogenhagen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/1d66dc4bfabb479694533af623a72a83
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