Functional significance of SRJ domain mutations in CITED2.

CITED2 is a transcriptional co-activator with 3 conserved domains shared with other CITED family members and a unique Serine-Glycine Rich Junction (SRJ) that is highly conserved in placental mammals. Loss of Cited2 in mice results in cardiac and aortic arch malformations, adrenal agenesis, neural tu...

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Autores principales: Chiann-mun Chen, Jamie Bentham, Catherine Cosgrove, Jose Braganca, Ana Cuenda, Simon D Bamforth, Jürgen E Schneider, Hugh Watkins, Bernard Keavney, Benjamin Davies, Shoumo Bhattacharya
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/1d877b3f3fcb4f5d8fbd3476886fbdc0
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