Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder

Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder

Epigenetic mechanisms have emerged as contributors to the molecular impairments caused by exposure to environmental factors such as abused substances. Here the authors perform epigenetic profiling of the striatum and identify the tyrosine kinase FYN is an important driver of neurodegenerative-like p...

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Autores principales: Gabor Egervari, Diana Akpoyibo, Tanni Rahman, John F. Fullard, James E. Callens, Joseph A. Landry, Annie Ly, Xianxiao Zhou, Noël Warren, Mads E. Hauberg, Gabriel Hoffman, Randy Ellis, Jacqueline-Marie N. Ferland, Michael L. Miller, Eva Keller, Bin Zhang, Panos Roussos, Yasmin L. Hurd
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/1d88bd91ce5342d1ae6c9fd044545db3
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https://doaj.org/article/1d88bd91ce5342d1ae6c9fd044545db3

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