Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage
Summary SOS box of the recA promoter, PVRecA from Vibrio natriegens was characterized, cloned and expressed in a probiotic strain E. coli Nissle 1917. This promoter was then rationally engineered according to predicted interactions between LexA repressor and PVRecA. The redesigned PVRecA‐AT promoter...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
Wiley
2021
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Subjects: | |
Online Access: | https://doaj.org/article/1d917eaa409b4fd6825382f017ee98bb |
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