SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores

The kinetochore-bound motor CENP-E plays a critical role in chromosome alignment. Here, the authors show that NF-κB activating protein (NKAP) dynamically localises to kinetochores, is SUMOylated during mitosis, and this modification is required for NKAP to bind CENP-E and localise CENP-E to the kine...

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Autores principales: Teng Li, Liang Chen, Juanxian Cheng, Jiang Dai, Yijiao Huang, Jian Zhang, Zhaoshan Liu, Ang Li, Na Li, Hongxia Wang, Xiaomin Yin, Kun He, Ming Yu, Tao Zhou, Xuemin Zhang, Qing Xia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1d9387d886e04cbf92521da9a468d7b2
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