SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores

SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores

The kinetochore-bound motor CENP-E plays a critical role in chromosome alignment. Here, the authors show that NF-κB activating protein (NKAP) dynamically localises to kinetochores, is SUMOylated during mitosis, and this modification is required for NKAP to bind CENP-E and localise CENP-E to the kine...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Teng Li, Liang Chen, Juanxian Cheng, Jiang Dai, Yijiao Huang, Jian Zhang, Zhaoshan Liu, Ang Li, Na Li, Hongxia Wang, Xiaomin Yin, Kun He, Ming Yu, Tao Zhou, Xuemin Zhang, Qing Xia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/1d9387d886e04cbf92521da9a468d7b2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares