Amyloid-β 25-35 Induces Neurotoxicity through the Up-Regulation of Astrocytic System X<sub>c</sub><sup>−</sup>
Amyloid-β (Aβ) deposition, a hallmark of Alzheimer’s disease, is known to induce free radical production and oxidative stress, leading to neuronal damage. During oxidative stress, several cell types (including astrocytes) can activate the nuclear factor erythroid 2-related factor 2 (Nrf2), a regulat...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
MDPI AG
2021
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| Accès en ligne: | https://doaj.org/article/1dc1c18c82e54289a339152b5689121f |
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