Estimating DNA methylation potential energy landscapes from nanopore sequencing data

Abstract High-throughput third-generation nanopore sequencing devices have enormous potential for simultaneously observing epigenetic modifications in human cells over large regions of the genome. However, signals generated by these devices are subject to considerable noise that can lead to unsatisf...

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Bibliographic Details
Main Authors: Jordi Abante, Sandeep Kambhampati, Andrew P. Feinberg, John Goutsias
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/1dd7b0607dc5416e8c94fe3f58dcf75f
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