Nrf2 regulates cell motility through RhoA–ROCK1 signalling in non-small-cell lung cancer cells

Abstract Nuclear factor-erythroid 2-related factor 2 (Nrf2) is a key transcriptional regulator of several antioxidant and anti-inflammatory enzymes. It binds to its endogenous inhibitor Kelch-like ECH-associated protein 1 (Keap1) in the cytoplasm under normal conditions. Various endogenous or enviro...

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Autores principales: Eunsun Ko, Dasom Kim, Dong Wha Min, Seung-Hae Kwon, Ji-Yun Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1e2ce9ed5c914ae19477f26689d4bc0f
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