Interplay of <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> <italic toggle="yes">fabZ</italic> and <italic toggle="yes">lpxC</italic> Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis
ABSTRACT Tight coordination of inner and outer membrane biosynthesis is very important in Gram-negative bacteria. Biosynthesis of the lipid A moiety of lipopolysaccharide, which comprises the outer leaflet of the outer membrane has garnered interest for Gram-negative antibacterial discovery. In part...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2018
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| Accès en ligne: | https://doaj.org/article/1e5ff2b427e345449955f5246fb5ce69 |
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