Refined efficacy estimates of the Sanofi Pasteur dengue vaccine CYD-TDV using machine learning
Clinical trials for the CYD-TDV dengue vaccine showed that vaccine efficacy varies with prior dengue exposure, but baseline serostatus is only known for 12% of subjects. Here, Dorigatti et al. use machine learning to impute baseline serostatus and determine vaccine efficacy by baseline serostatus, a...
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Auteurs principaux: | , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/1e68c8a00b6d4e3c8a2064bb9e95ef0a |
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