Scientific Opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species

Abstract Naringin, a flavanone glycoside, occurs naturally in the pericarp of citrus fruit, and particularly of grapefruit (Citrus paradisii) where it is the predominant flavanoid found and is responsible for the bitter taste associated with the fruit. It is currently listed in the register of flavo...

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Autor principal:	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2011
Materias:	Sensory additive flavourings flavanones naringin safety Nutrition. Foods and food supply TX341-641 Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/1ec5523285044bc5b83e426dd0b23cdd
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spelling	oai:doaj.org-article:1ec5523285044bc5b83e426dd0b23cdd2021-12-01T10:05:38ZScientific Opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species1831-473210.2903/j.efsa.2011.2416https://doaj.org/article/1ec5523285044bc5b83e426dd0b23cdd2011-11-01T00:00:00Zhttps://doi.org/10.2903/j.efsa.2011.2416https://doaj.org/toc/1831-4732Abstract Naringin, a flavanone glycoside, occurs naturally in the pericarp of citrus fruit, and particularly of grapefruit (Citrus paradisii) where it is the predominant flavanoid found and is responsible for the bitter taste associated with the fruit. It is currently listed in the register of flavouring substances, allowing its use in food without restriction. Data from chronic oral feeding studies in rats indicated that a use level up to 5 mg naringin/kg complete feed is safe for all animal species with a considerable margin of safety. Based on mammalian data, only transient amounts of residues of naringin and metabolites in animal tissues or products derived from the use of naringin are to be expected. This would represent an insignificant contribution to human exposure. Consequently, the use of naringin in animal nutrition is considered safe for the consumer. No data relevant for assessing user safety was made available. The applicant considers that the additive in the solid form is a possible eye and respiratory irritant. The use of naringin in animal nutrition is not expected to pose a risk for the environment. Since its function in feed is essentially the same as that in food, no further demonstration of efficacy is considered necessary. However, in the absence of data the FEEDAP Panel could not conclude on the safety and efficacy of the product when delivered in water for drinking. In particular, the FEEDAP Panel is concerned about the potential release of the aglycone, the loss of sensory characteristics and the availability of carbohydrate for microbial growth.EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)WileyarticleSensory additiveflavouringsflavanonesnaringinsafetyNutrition. Foods and food supplyTX341-641Chemical technologyTP1-1185ENEFSA Journal, Vol 9, Iss 11, Pp n/a-n/a (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Sensory additive flavourings flavanones naringin safety Nutrition. Foods and food supply TX341-641 Chemical technology TP1-1185
spellingShingle	Sensory additive flavourings flavanones naringin safety Nutrition. Foods and food supply TX341-641 Chemical technology TP1-1185 EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Scientific Opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species
description	Abstract Naringin, a flavanone glycoside, occurs naturally in the pericarp of citrus fruit, and particularly of grapefruit (Citrus paradisii) where it is the predominant flavanoid found and is responsible for the bitter taste associated with the fruit. It is currently listed in the register of flavouring substances, allowing its use in food without restriction. Data from chronic oral feeding studies in rats indicated that a use level up to 5 mg naringin/kg complete feed is safe for all animal species with a considerable margin of safety. Based on mammalian data, only transient amounts of residues of naringin and metabolites in animal tissues or products derived from the use of naringin are to be expected. This would represent an insignificant contribution to human exposure. Consequently, the use of naringin in animal nutrition is considered safe for the consumer. No data relevant for assessing user safety was made available. The applicant considers that the additive in the solid form is a possible eye and respiratory irritant. The use of naringin in animal nutrition is not expected to pose a risk for the environment. Since its function in feed is essentially the same as that in food, no further demonstration of efficacy is considered necessary. However, in the absence of data the FEEDAP Panel could not conclude on the safety and efficacy of the product when delivered in water for drinking. In particular, the FEEDAP Panel is concerned about the potential release of the aglycone, the loss of sensory characteristics and the availability of carbohydrate for microbial growth.
format	article
author	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
author_facet	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
author_sort	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
title	Scientific Opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species
title_short	Scientific Opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species
title_full	Scientific Opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species
title_fullStr	Scientific Opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species
title_full_unstemmed	Scientific Opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species
title_sort	scientific opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species
publisher	Wiley
publishDate	2011
url	https://doaj.org/article/1ec5523285044bc5b83e426dd0b23cdd
work_keys_str_mv	AT efsapanelonadditivesandproductsorsubstancesusedinanimalfeedfeedap scientificopiniononthesafetyandefficacyofnaringinwhenusedasasensoryadditiveforallanimalspecies
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Scientific Opinion on the safety and efficacy of naringin when used as a sensory additive for all animal species

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