Structural Basis for Linezolid Binding Site Rearrangement in the <italic toggle="yes">Staphylococcus aureus</italic> Ribosome
ABSTRACT An unorthodox, surprising mechanism of resistance to the antibiotic linezolid was revealed by cryo-electron microscopy (cryo-EM) in the 70S ribosomes from a clinical isolate of Staphylococcus aureus. This high-resolution structural information demonstrated that a single amino acid deletion...
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Autores principales: | , , , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/1ec9f31a43344b03be4992f9b65c601b |
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