Angiotensin II promotes the anticoagulant effects of rivaroxaban via angiotensin type 2 receptor signaling in mice

Abstract Rivaroxaban is an oral direct factor Xa inhibitor approved for the treatment of stroke and systemic thromboembolism in patients with non-valvular atrial fibrillation. Despite its efficacy, rivaroxaban therapy results in adverse effects and complications, such as bleeding. Angiotensin II (An...

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Auteurs principaux: Dan Yang, Junjie Shao, Ruifeng Hu, Haimei Chen, Ping Xie, Chang Liu
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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R
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Accès en ligne:https://doaj.org/article/1ed48557023c41f4b6b512cdc3b6a862
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