BST2/Tetherin enhances entry of human cytomegalovirus.

Interferon-induced BST2/Tetherin prevents budding of vpu-deficient HIV-1 by tethering mature viral particles to the plasma membrane. BST2 also inhibits release of other enveloped viruses including Ebola virus and Kaposi's sarcoma associated herpesvirus (KSHV), indicating that BST2 is a broadly...

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Auteurs principaux: Kasinath Viswanathan, M Shane Smith, Daniel Malouli, Mandana Mansouri, Jay A Nelson, Klaus Früh
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/1ede8b7d00e648df9b409b2af55bef5a
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