An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism

An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism

The use of synthetic organisms could provide opportunities for discovery and advanced manufacturing of medical drugs. Here the authors use a semi-synthetic organism with an expanded genetic code to generate site-specific chemical modifications in human IL-2.

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Detalles Bibliográficos
Autores principales: Jerod L. Ptacin, Carolina E. Caffaro, Lina Ma, Kristine M. San Jose Gall, Hans R. Aerni, Nicole V. Acuff, Rob W. Herman, Yelena Pavlova, Michael J. Pena, David B. Chen, Lilia K. Koriazova, Laura K. Shawver, Ingrid B. Joseph, Marcos E. Milla
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/1eeb5f339edc4637a3c9f0f0c17dcf95
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https://doaj.org/article/1eeb5f339edc4637a3c9f0f0c17dcf95

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